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09. MMC and HIV Positive men

South African National HIV Prevalence, Incidence and Behaviour Survey, 2012. Human Sciences Research Council (HSRC)

The 2012 population-based survey of HIV prevalence is the fourth in the series of national HIV prevalence surveys that have investigated HIV prevalence and behaviour. In 2002, a consortium consisting of the Human Sciences Research Council (HSRC), Medical Research Council (MRC), Centre for AIDS Development, Research and Evaluation (CADRE) and Agence Nationale de Recherche sur le Sida (ANRS) constituted the first research team to conduct a national population-based survey of HIV prevalence in South Africa. Since 2002, the HSRC and its partners, supported by different international and local donors, have conducted several national surveys that have contributed to the country’s understanding of the HIV epidemic over time (Shisana & Simbayi, 2002; Shisana, Rehle, Simbayi et al. 2005; Shisana, Rehle, Simbayi et al. 2009).

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The Safety of Adult Male Circumcision in HIV-Infected and Uninfected Men in Rakai, Uganda

(42) Kigozi G, Gray RH, Wawer MJ, et al. The safety of adult male circumcision in HIV-infected and uninfected men in Rakai, Uganda. PLoS Med. 2008;5:e116.
The objective of the study was to compare rates of adverse events (AEs) related to male circumcision (MC) in HIV-positive and HIV-negative men in order to provide guidance for MC programs that may provide services to HIV-infected and uninfected men.

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The Safety of Adult Male Circumcision in HIV Infected and Uninfected Men in Rakai, Uganda

Kigozi G et al. The Safety of adult male circumcison in HIV-infected and uninfected men in Rakai, Uganda. PLoS Med. 2008

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HIV shedding from male circumcision wounds in HIV-infected men: a prospective cohort study

A randomised trial of voluntary medical male circumcision (VMMC) of HIV-infected men reported increased HIV transmission to female partners among men who resumed sexual intercourse prior to wound healing. Penile HIV shedding is significantly reduced after healing of MMC wounds. Starting ART prior to MMC should be considered to reduce male-to-female HIV transmission risk. Research is needed to assess the time on ART required to decrease shedding, and the acceptability and feasibility of initiating ART at the time of MMC.

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